Clinicaltrials.gov was searched for registered review protocols. The keywords “palmitoylethanolamide” and “pain” resulted in 13 entries, of which 3 were being concluded. None of them fulfilled our eligibility conditions. The anti‐inflammatory results of PEA appear to be largely connected to its ability to modulate mast cell activation and degranulation, https://martinuxvur.shotblogs.com/the-basic-principles-of-palmitoylethanolamide-44680949