Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors from the central anxious process, conolidine modulates alternate molecular targets. A Science Advancements research found that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://judahulsfr.wssblogs.com/37530211/alternative-natural-pain-relief-to-replace-traditional-painkillers-for-dummies